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recently, scientists have discovered that certain components of marijuana,
including CBD, are responsible for its pain-relieving
effects. The human body contains a specialized system called the
endocannabinoid system (ECS), which is involved in regulating a variety of
functions including sleep, appetite, pain and immune system response. The body
produces endocannabinoids, which are neurotransmitters that bind to cannabinoid
receptors in your nervous system. Studies have shown that CBD may help reduce
chronic pain by impacting endocannabinoid receptor activity, reducing
inflammation and interacting with neurotransmitters. For example, one study in
rats found that CBD injections reduced pain response to surgical incision,
while another rat study found that oral CBD treatment significantly reduced
sciatic nerve pain and inflammation. Several human studies have found that a
combination of CBD and THC is effective in treating pain related to multiple
sclerosis and arthritis. An oral spray called Sativex, which is a combination
of THC and CBD, is approved in several countries to treat pain related to
multiple sclerosis. In a study of 47 people with multiple sclerosis, those
treated with Sativex for one month experienced a significant improvement in
pain, walking and muscle spasms, compared to the placebo group. Another study
found that Sativex significantly improved pain during movement, pain at rest
and sleep quality in 58 people with rheumatoid arthritis.
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